J35.2 J35.1 U07.1
Conditions
Interventions
Group 1: For the planned project we will collect clinical variables, tissue, SARS-CoV-2-antigen and -PCR swabs. Parents are asked to carry out a SARS-CoV-2 antigen rapid test in the oropharynx and in
Sponsors
St. Elisabeth Krankenhaus
Eligibility
Sex/Gender
All
Age
0 Years to 6 Years
Inclusion criteria
Inclusion criteria: - Children = 6 years - Planned adenotomy and/or tonsillotomy under general anesthesia - Consent from a parent to participate in the study
Exclusion criteria
Exclusion criteria: - Positive preoperative SARS-CoV-2 PCR swab - Participation in another clinical study within the last month prior to study entry
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Negative predictive value of a SARS-CoV-2 PCR test in small children: SARS-CoV-2 rapid antigen test naso- and oropharynx (preoperative and intraoperative), PCR smear in the nasopharynx and oropharynx (preoperative), PCR smear in the oropharynx and nasopharynx and on removed tissue (separately, intraoperative), SARS-CoV-2 antibodies in serum (intraoperative, 5 ml serum) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Prevalence of COVID-19 in young children. - Differences between oropharyngeal and nasopharyngeal swabs in this patient group. - Value of parental self-tests and rapid intraoperative tests. | — |
Countries
Germany
Contacts
Public ContactStijn Bogaert
St. Elisabeth Krankenhaus, Bochum
Outcome results
None listed