C50.9
Conditions
Interventions
Group 1: Patients with confirmed breast carcinoma and current mammography/tomosynthesis or clinical indication for mammography/tomosynthesis and clinical indication for CT thorax with contrast. In add
Sponsors
Department of Radiology, Medical Center - University of Freiburg
Eligibility
Sex/Gender
Female
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: - Group A: Patients with confirmed breast carcinoma and current mammography/tomosynthesis or clinical indication for mammography/tomosynthesis and clinical indication for CT thorax with contrast medium - Group B: Patients without breast carcinoma with current mammography/tomosynthesis or clinical indication for mammography/tomosynthesis and clinical indication for CT thorax with contrast medium due to other diseases.
Exclusion criteria
Exclusion criteria: Lack of recent mammography (not available, no current clinical indication or not feasible) - Contraindication to contrast medium used - Prone position not possible for health reasons (necessary for CT and, in the case of group A, for MRI examination) - Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the presence of breast cancer on PCCT for each breast by breast radiologists blinded to patient data (sensitivity, specificity of PCCT). | — |
Secondary
| Measure | Time frame |
|---|---|
| - Size of breast cancer in PCCT (maximal diameter and volumetry) and - Spread of breast cancer in PCCT (single, multicentric or multifocal) evaluated for each breast by breast radiologists blinded for patient data - Positive margin resection rate | — |
Countries
Germany
Contacts
Public ContactJakob Neubauer
Department of Radiology, Medical Center - University of Freiburg
Outcome results
None listed