Detection of cerebral hyperperfusion syndrome via extracranial sonographic measurement of cerebral bloodflow-volume in patients after mechanical therapy in ischemic stroke with large vessel occlusion

Detection of cerebral hyperperfusion syndrome via extracranial sonographic measurement of cerebral bloodflow-volume in patients after mechanical therapy in ischemic stroke with large vessel occlusion - DETECT-CHS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00028985

Enrollment

Registered

2022-12-22

Start date

2022-11-23

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63.3 I61.2

Interventions

Group 1: Extracranial sonographic blood flow volumetry of the A. carotis interna

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: -Ischemic stroke with occlusion of the Internal Carotid Artery and/or Middle Cerebral Artery in segment M1 -Age >18 years -mechanical recanalization = TICI 2b (± Stent)

Exclusion criteria

Exclusion criteria: - technically indiced injury of the vessel (dissection, perforation, rupturation) - significant stenosis common carotid artery, internal carotid artery (NASCET >50%) or middle cerbral artery in segment M1 - lack of visualization of the middle cerebral artery in segment M1

Design outcomes

Primary

Measure	Time frame
Investigation of the diagnostic quality criteria of SEBFV in comparison to TCD as a standard method for the detection of CHS (sensitivity, specificity each with 95% confidence interval, positive predictive value, negative predictive value, kappa-coefficient, ROC-analysis).	—

Secondary

Measure	Time frame
mRS 90 days after stroke	—

Countries

Germany

Contacts

Public ContactWolf-Dirk Niesen

Klinik für Neurologie und Neurophysiologie Universitätsklinikum Freiburg

wolf-dirk.niesen@uniklinik-freiburg.de076127050010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026