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Crossover in vivo study: investigation of the redox status of study participants before and after ingestion of vitamin C in blood.

Crossover in vivo study: investigation of the redox status of study participants before and after ingestion of vitamin C in blood.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00028934
Enrollment
20
Registered
2022-05-11
Start date
2020-10-28
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Group 1: Blood is drawn from the study participants before the start of the study (V1). The characterization results of the V1 blood serve as the basis for all follow-up examinations (= baseline). Ea

Sponsors

Charité-Universitätsmedizin Berlin, Dermatologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria The studies will be conducted on study participants who - are healthy - are between 20 and 60 years old - Are informed about the aims of the study and the nature of the investigations - your informed consent to participate, have given in writing.

Exclusion criteria

Exclusion criteria: Exclusion criteria: With exception of - Persons with allergies or intolerance reactions to food - Children - Pregnant and nursing mothers - Individuals who have given their informed consent have not given in writing - Persons who are not self-responsible can make decisions - Charité students in the exam semester

Design outcomes

Secondary

MeasureTime frame
Finally, a method for determining the redox status in blood after UV stress induction for electron spin resonance (ESR) spectroscopy is to be developed, which can determine the redox status in blood and assess the supply of antioxidants. Finally, a method for determining the redox status in blood after UV stress induction for electron spin resonance (ESR) spectroscopy is to be developed, which can determine the redox status in blood and assess the supply of antioxidants.

Primary

MeasureTime frame
The in vivo study aims to show that increasing the dose of vitamin C in physiological concentrations leads to antioxidant protection that can be quantitatively/qualitatively demonstrated in the blood. However, if the critical vitamin C concentration is exceeded, there can be an increased formation of free radicals (prooxidative effect) in the blood.

Countries

Germany

Contacts

Public ContactSilke Lohan

Charité – Universitätsmedizin Berlin Department of Dermatology, Venereology and Allergology Center of Experimental and Applied Cutaneous Physiology

silke.lohan@charite.de+49 (030) 450 518 235

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026