Prognostic impact of serum concentrations of NSE and S-100 in patients after cardiac surgery due to type A aortic dissection

Prognostic impact of serum concentrations of NSE and S-100 in patients after cardiac surgery due to type A aortic dissection - ProgN0stA

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00028926

Enrollment

Registered

2022-05-16

Start date

2022-05-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I71.0 T82

Interventions

Group 1: Patients with a type A aortic dissection, who undergo surgery. Prior to surgery blood samples will be taken of the patients. This provides reference levels for the postoperative blood levels

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: type A aortic dissection, that needs to be treated

Exclusion criteria

Exclusion criteria: preoperative resuscitation due to this dissection/ no letter of acceptance

Design outcomes

Primary

Measure	Time frame
Is there a correlation of the postoperative NSE- and Protein S-100-levels, which will be taken for five days after the surgery, and the neurological outcome of the patient at the day he gets discharged of hospital? The neurological outcome will be evaluated with a SIDAM-test. The test will be taken the same day the patient will be discharged.	—

Secondary

Measure	Time frame
Could the establishment of NSE and/or Protein S-100 serve as a predictive marker in cases of surgical intervention of type A aortic dissection?	—

Countries

Germany

Contacts

Public ContactEva Eriksson

Uniklinikum Regensburg

Eva.Eriksson@stud.uni-regensburg.de0941 94419831

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026