Munich Adiposity Rescue Study (MARS): Endoscopic Sleeve Gastroplasty and Laparoscopic Sleeve Gastrectomy as Safe Bariatric Interventions in Children with Morbid Obesity - A Long-Term Head to Head Pilot Study with Focus on Safety.

Munich Adiposity Rescue Study (MARS): Endoscopic Sleeve Gastroplasty and Laparoscopic Sleeve Gastrectomy as Safe Bariatric Interventions in Children with Morbid Obesity - A Long-Term Head to Head Pilot Study with Focus on Safety. - MARS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00028882

Enrollment

Registered

2022-05-10

Start date

2023-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66.05

Interventions

Group 1: Laparoscopic sleeve gastrectomy (n=15): Baseline examination and follow-up examination 14 days, 28 days, 1 year, 2 years, 3 years, 4 years and 5 years after intervention. Assessment of prim

Eligibility

Sex/Gender

All

Age

12 Years to 18 Years

Inclusion criteria

Inclusion criteria: Morbid obesity: BMI =40 kg/m2 or BMI =35 kg/m2 with the presence of =2 comorbidities (e.g., NASH, arterial hypertension, type 2 diabetes).

Exclusion criteria

Exclusion criteria: Age at initial contact: 18 years. Celiac disease, Wilson's disease, hepatitis A, B, C, E, A1AT deficiency, autoimmune hepatitis, hemochromatosis, acute infection, psychomotoric retardation, type 1 diabetes. Reduction/maintenance of bodyweight by non-interventional therapies with a duration of =6 months before study inclusion.

Design outcomes

Primary

Measure	Time frame
Bodyweight in kilogram at baseline examination and at follow up examination 14 days, 28 days, 1 year, 2 years, 3 years, 4 years and 5 years after intervention. Periinterventional complications (e.g., injuries, infections, duration of procedure), postinterventional complications (e.g., injuries, duration of intensive care treatment, duration of inpatient treatment, pain diary) 14 days after intervention.	—

Measure

Time frame

Bodyweight in kilogram at baseline examination and at follow up examination 14 days, 28 days, 1 year, 2 years, 3 years, 4 years and 5 years after intervention. Periinterventional complications (e.g., injuries, infections, duration of procedure), postinterventional complications (e.g., injuries, duration of intensive care treatment, duration of inpatient treatment, pain diary) 14 days after intervention.

—

Secondary

Measure	Time frame
Cardiovascular outcome, metabolic outcome, gastrointestinal outcome, mental outcome	—

Countries

Germany

Contacts

Public ContactOliver;Eberhard Muensterer;Lurz

Kinderchirurgische Klinik und Poliklinik im Dr. von Haunerschen Kinderspital;Abteilung für Pädiatrische Gastroenterologie und Hepatologie, Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital

oliver.muensterer@med.uni-muenchen.de;eberhard.lurz@med.uni-muenchen.de+49 89 4400-53101;+49 89 4400-53679

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026