intraoperative repolarisation disturbances - aetiology and relevance for anesthesiological decision-making in volume management and blood transfusion

intraoperative repolarisation disturbances - aetiology and relevance for anesthesiological decision-making in volume management and blood transfusion - Qt Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00028851

Enrollment

Registered

2024-09-04

Start date

2014-01-06

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

open retroperitoneal urological surgeries D62 E86

Interventions

Group 1: QT-time registration by patients during general anaesthesia with propofol Group 2: QT-time registration by patients during general anaesthesia with desflurane

Eligibility

Sex/Gender

Male

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - ASA I, II - Urological operations in general anaesthesia with thoracic epidural analgesia - Competent, full aged patients - written consent

Exclusion criteria

Exclusion criteria: - female - ASA III, IV - diabetes mellitus - coronary heart disease - LVEF I° - drug abuses - preoperative existing electrolyte disturbances - chronic renal failure > II° - liver cirrhosis > Child-Pugh-Score A - elevated fT3, fT4 - Hypophysis insufficiency - neuroendocrine tumours - Anorexia nervosa (BMI I° - preoperative QT lengthening medication - preoperative haemoglobin < 6.0 mmol/l - HIV infection

Design outcomes

Primary

Measure	Time frame
Effect of intraoperative blood loss in qt-time variation: Registration of qt-time variation after intraoperative surgical blood loss deltaQT (ms) at the time of blood loss	—

Secondary

Measure	Time frame
Normalizing of QT changes after correction of hypovolaemia	—

Countries

Germany

Contacts

Public ContactJuliane Ende

Universitätsklinikum Carl Gustav Carus Dresden

Juliane.Ende@uniklinikum-dresden.de+35145817371

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026