K05.3 K05.4
Conditions
Interventions
Group 1: subgingival instrumentation (SI) of all sites with probing pocket depth >/= 4 mm without adjunctive systemic antibiotics
Group 2: subgingival instrumentation (SI) of all sites with probing po
in case of intolerance to penicillin 250 mg ciprofloxacin and 500 mg metronidazole 2 times daily for 7 days)
Sponsors
Poliklinik für Parodontologie,ZZMK (Carolinum) der Johann Wolfgang Goethe-Universität Frankfurt a.M.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Patients of the Dept. of Periodontology having received comprehensive periodontal treatment between January 2008 band December 2018; - Results of microbiological testing of subgingival biofilm prior to treatment (T0); - Complete periodontal examination prior to periodontal treatment (T0) and 6 weeks to 3 months thereafter (T1) including probing pocket depths (PPD) and vertical clinical attachment level (CAL-V) at 6 sites/tooth; - Radiographs depicting the whole dentition at start of periodntal treatment (not older than 6 months at T0).
Exclusion criteria
Exclusion criteria: Incomplete or missing data (periodontal charts, radiographs and/or microbiological test reports)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Achievement of “treat-to-target” endpoint, e.g. =4 sites with probing pocket depths =5 mm (Feres et al., 2020) 6 weeks to 3 months after SI (T1) | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of sites with PPD =3 mm, 4 to 5 mm, =6 mm at T0, T1 and (T2); Number of patients treated adjunctively with systemic antibiotics according to recent concept (2004-2018) and according to 2018 guide line. | — |
Countries
Germany
Contacts
Public ContactPeter Eickholz
Poliklinik für Parodontologie,ZZMK (Carolinum) der Johann Wolfgang Goethe-Universität Frankfurt a.M.
Outcome results
None listed