K57 C18
Conditions
Interventions
Group 1: Intervention group: The participants will conduct three times a week over 3-5 weeks a combined endurance and resistance training. Each training session will take 60 minutes and will be super
Sponsors
Abteilung "Leistung und Gesundheit (Sportmedizin)"Institut für Sport und SportwissenschaftTechnische Universität DortmundOtto-Hahn-Straße 3, 44227 Dortmund
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: - Diagnosis of acute or chronic diverticulitis or colon cancer - Candidate for elective colorectal surgery - Schedule of surgery that allows intervention of more than three to five weeks prior to surgery - High risk for surgical complications, defined by the presence of concomitant diseases such as deconditioning, heart disease, diabetes, renal insufficiency, hypertension or severe obesity (BMI=30) - German language skills that allow understanding of the questionnaires and the tasks during testing and the sports intervention
Exclusion criteria
Exclusion criteria: Non-elective surgery Unstable heart or respiratory disease Limitations in mobility that prevent the intended exercise training Cognitive limitations that prevent participation in the programme Participation in other research studies that affect the endpoint of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endurance capacity measured by 6 Minute Walking Test at t0, t1, t3, t4 and t5 | — |
Secondary
| Measure | Time frame |
|---|---|
| Peak oxygen uptake (VO2peak) reflecting their cardiorespiratory fitness measured during a maximal incremental exercise test on a cycle ergometer (t0, t1, t4 and t5) Strength capacity measured by the Five-Repetition Maximum strength in relevant muscle groups (0, t1, t4 and t5) and by the hand grip strength (t0, t1, t3, t4 and t5) body composition measured by a bioimpedance analysis (t0, t1, t4 and t5) clincal, patient- oriented outcomes, i.e. days at home after 30, 60 and 90 days post surgery, time of intensive care needed, postoperative complicationes, return to work (t3, t4 and t5) questionnaires to measure sleeping quality (t0, t1, t4 and t5) and quality of life (t0, t1, t4 and t5) Number and proportions of further circulating immune markers associated with inflammation and exercise (t0, t1, t2, t3, t4 and t5) Systemic and local, humoral and cellular inflammatory markers in blood, visceral fat and intestinal tissue (t2) | — |
Countries
Germany
Contacts
Public ContactMarit Lea Schlagheck
Abteilung "Leistung und Gesundheit (Sportmedizin)"Institut für Sport und SportwissenschaftTechnische Universität Dortmund
Outcome results
None listed