Heart rate variability-based biofeedback in patients after acute COVID-19 disease

Heart rate variability-based biofeedback in patients after acute COVID-19 disease - POSTCOVID-BIOFEEDBACK 001

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00028715

Enrollment

Registered

2022-04-21

Start date

2022-01-16

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

B34.2

Interventions

Group 1: HRV-biofeedbacktraining, 9 times in 12 days Group 2: Sham-biofeddbacktraining, 9 times in 12 days

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: proof of SARS-CoV-2 infection; clinically remission of a no longer infectious COVID-19 disease; persistent cardiopulmonary symptomatic disease with indication for further inpatient or early rehabilitative therapy

Exclusion criteria

Exclusion criteria: taking tricyclic antidepressants within 14 days before start of study participation; arrhythmia absoluta; pacemakers; known diabetic or autonomic neuropathy; alcohol dependence; respiratory failure; cognitive deficits or physical limitations with resulting inability to perform biofeedback training

Design outcomes

Primary

Measure	Time frame
Heart rate variability assessed via standard deviation of NN intervals (SDNN)	—

Secondary

Measure	Time frame
HRV frequency-, and time domain parameters, sudomotor and vasomotor function as well as degree of COVID-19-associated symptoms	—

Countries

Germany

Contacts

Public ContactErik Simon

Universitätsklinikum Dresden,Carl Gustav CarusKlinik und Poliklinik für Neurologie

Erik.Simon@ukdd.de+4935145818506

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026