Z42.1 C81
Conditions
Interventions
Group 1: Breast reconstruction in Hodgkin lymphoma survivors who received chest radiotherapy
Group 2: Breast reconstruction in matched controls without a history of Hodgkin lymphoma or chest radiother
Sponsors
Department of Plastic and Reconstructive Surgery, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Group 1: Breast reconstructions in Hodgkin survivors diagnosed with BC after previous chest radiotherapy for Hodgkin and who had undergone BR after therapeutic or prophylactic mastectomy. Group 2: Control breast reconstructions after therapeutic or prophylactic mastectomy in patients without a history of HL or chest radiotherapy were matched to patients in group 1 on age at mastectomy (±five years), date of BR (±five years), and type of BR (direct-to-implant; tissue expander/implant; autologous with implant; autologous only) and timing of BR (immediate or delayed).
Exclusion criteria
Exclusion criteria: Breasts which had received radiotherapy for BC before BR were excluded. Patients were excluded if their electronic health records had missing data regarding supradiaphragmatic radiotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| complication-related breast reconstruction failure or conversion | — |
Secondary
| Measure | Time frame |
|---|---|
| complication-related re-operation, capsular contracture, major donor-site complications, and complication-related ICU admission | — |
Countries
Netherlands
Contacts
Public ContactM.A.M. Mureau
Department of Plastic and Reconstructive Surgery, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands
Outcome results
None listed