Efficacy of near-infrared spectroscopy cerebral oximetry on detecting ischemia during cross-clamping of the internal carotid artery - a prospective observational study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00028613

Enrollment

200

Registered

2022-03-24

Start date

2022-02-16

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63.5

Interventions

Group 1: - Before induction of anesthesia, in addition to basic monitoring, bifrontal cerebral oximetry (Masimo Root O3 system) and a bifrontal processed EEG (Masimo Root PSi) are applied - Before in

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Pre-existing asymptomatic or symptomatic ACI stenosis - planned surgical treatment of an ACI-TEA under general anesthesia in the UHZ of the UKE unrelated to this study

Exclusion criteria

Exclusion criteria: - Age < 18 years - Insufficient signal quality of the mSSEP or NIRS values

Design outcomes

Primary

Measure	Time frame
- Incidence of ischemia during carotid cross-clamping (mSSEP decrease >50% below baseline or an mSSEP latency extension of at least 10-20% of the respective baseline values before clamping)	—

Secondary

Measure	Time frame
- Incidence of a NIRS drop without mSSEP drop - Incidence of postoperative delirium - Postoperative incidence of new focal neurological deficits - Incidence of hyperperfusion syndrome after ACI-TEA	—

Countries

Germany

Contacts

Public ContactKristen Thomsen

Universitätsklinikum Hamburg Eppendorf

kr.thomsen@uke.de+4915222818167

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026