Point of care assessment in acute ischemic stroke with intravenous thrombolysis and/or history of direct oral anticoagulation medication – a prospective observational study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00028597

Enrollment

1850

Registered

2022-03-22

Start date

2022-10-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I64

Interventions

Group 1: Enhanced blood coagulation monitoring will be performed in participants at hospital admission and on 5 time points after intravenous thrombolysis. Patient, who were not eligible for intraveno

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Hospital admission at university hospital Dresden with suspected for stroke any cause.

Exclusion criteria

Exclusion criteria: Schwerwiegende hereditäre Blutungsneigung.

Design outcomes

Primary

Measure	Time frame
The primary endpoint is defined as combined endpoint up to 48h after intravenous thrombolysis, e.g. bleeding or recurrent thrombosis.	—

Secondary

Measure	Time frame
Secondary outcomes are patients survival during in hospital stay and the incidence of any thromboembolic complication. Furthermore, results of conventional laboratory analyzes and viscoelastic testing regarding the diagnostic accuracy of detecting direct oral anti-coagulation drugs will be compared.	—

Countries

Germany

Contacts

Public ContactLars Heubner

Universitätsklinikum Carl Gustav CarusKlinik und Poliklinik für Anästhesiologie und Intensivtherapie

lars.heubner@ukdd.de0351-458-11660

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026