Comparison of two analgetic-regiments in neurosurgical spinal fusions and the effect of these on the postoperative opioid consumption

Comparison of two analgetic-regiments in neurosurgical spinal fusions and the effect of these on the postoperative opioid consumption - "iSpine"

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00028592

Enrollment

100

Registered

2022-03-21

Start date

2022-06-03

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M47 M54

Interventions

Group 1: intravenous analgesia Group 2: intravenous analgesia with an intrathecal singleshot

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. given written informed consent 2. elective dorsal spinal fusion at th10 and downwards, maximum of 3 levels 3. age >18 years

Exclusion criteria

Exclusion criteria: 1. No written informed consent 2. Age 3 weeks and >70 mg oral morphin äquivalent 5. no german speakers 6. not able to give informed consent 7. not allowing the saving and using of personal, medical data

Design outcomes

Primary

Measure	Time frame
Cumulative opioid consumption after 24 hours per patient, calculated in oral morphin äquivalents.	—

Secondary

Measure	Time frame
1. overall opioid consumption after 36 / 48 hours 2. PONV on the first / second postoperative days 3. time of first defacation 4. length of stay in post anesthesia ward 5. intensity of pain between patients 6. length of hospital stay 7. complications (respiratory failure, emergency surgery, postoperative infection, thrombosis) 8. measurement of inflammatory blood parameters before/after surgery, after 24 and 72 hours. 9. postoperative mobilisation with the physiotherapists	—

Measure

Time frame

1. overall opioid consumption after 36 / 48 hours 2. PONV on the first / second postoperative days 3. time of first defacation 4. length of stay in post anesthesia ward 5. intensity of pain between patients 6. length of hospital stay 7. complications (respiratory failure, emergency surgery, postoperative infection, thrombosis) 8. measurement of inflammatory blood parameters before/after surgery, after 24 and 72 hours. 9. postoperative mobilisation with the physiotherapists

—

Countries

Germany

Contacts

Public ContactSascha Treskatsch

Klinik für Anästhesie und operative IntensivmedizinCampus Benjamin FranklinCharité - Universitätsmedizin Berlin

sascha.treskatsch@charite.de030 450551522

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026