Catheter-associated infection/Catheter-associated bloodstream infection (CRBSI) Catheter dysfuntion
Conditions
Interventions
Group 1: Retrospective study, data was collected from a single Italian centre for 25 patients. All patients had solid cancers of different organs and uncomplicated CRBSI verified by differential time
Sponsors
Centro di Riferimento Oncologico di Avioano (CRO)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Implanted VAD - Clinical symptoms of fever and/or chills and blood tests compatible with catheter-colonization or with uncomplicated CRBSI (increased PCT, positive blood cultures from port/and/or peripheral vein)
Exclusion criteria
Exclusion criteria: - Not provided informed consent to use clinical data for study purposes - Lack of documentation of required data in the medical records - Patients with fungal or port-pocket infections - Patients with VAD removed due to clinical instability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Catheter salvage rate after adjuvant treatment with Geistlich TauroSept®: percentage of patients with negative blood culture 48 h after treatment in relation to the total number of treated patients | — |
Secondary
| Measure | Time frame |
|---|---|
| - Incidence of catheter occlusions - Incidence of catheter-related venous thrombosis - Incidence of infectious events after treatment - Number and frequency of catheter removals due to events related to the investigational device or investigational procedure - Days of VAD permanence after use of Geistlich TauroSept® - Removal of VAD due to treatment end - Patient death - Infection-free catheter survival - Overall catheter survival (combined endpoint composed of catheter infection and occlusion) | — |
Countries
Italy
Contacts
Public ContactFabrizio Brescia
Centro di Riferimento Oncologico di Avioano (CRO)
Outcome results
None listed