U08.9 LONG COVID
Conditions
Interventions
Group 1: Work package 1 will study 150 children and adolescents aged 6-18 years who present to the Long Covid outpatient clinic following referral by their pediatrician.
Sponsors
Universitätsklinik Jena
Eligibility
Sex/Gender
All
Age
6 Years to 17 Years
Inclusion criteria
Inclusion criteria: -Consent to data collection and examination/archiving of biomaterials -Boys and girls who meet diagnostic criteria for Long Covid: Evidence of previous SARS-CoV-2 infection (pos. SARS-CoV-2 PCR test and/or pos. SARS-CoV-2 antibody and a definite contact with a person with proven SARS-CoV-2 infection). and Presence of one or more symptoms compatible with Long COVID persisting longer than 4 weeks after infection and/or setting new on after initial recovery and relevant impairment of activities of daily life and no evidence for other causes wich could explain symptoms
Exclusion criteria
Exclusion criteria: - Pregnancy - Diagnosis of a disease that explains part of the symptoms and arose independently of the SARS CoV-2 infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary objective: Characterization of Long COVID-19 according to clinical, laboratory, functional and psychological aspects. Correlation to measurable organ damage, influence on quality of life. Main parameter: change in quality of life caused by Long COVID-19 in childhood and adolescence, measured with SF 12. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objectives/questions: What clues to the pathogenesis of long covid-19 can be elicited? What is the course of the disease? Can diagnostic criteria be established, or refined? Correlation to comorbidities. Correlation of functional diagnostics and laboratory with symptoms/suffering. Identification of disease-specific biomarkers. Secondary outcome measures: Clinical, laboratory, functional, and psychological changes at initial presentation and 3-month follow-up. | — |
Countries
Germany
Contacts
Public ContactDaniel Vilser
Klinik für Kinder und JugendmedizinUniversitätsklinikum Jena
Outcome results
None listed