None
Conditions
Interventions
Group 1: In the present project, different chemosensory functions as well as responses to chemosensory substances will be investigated: emotional evaluation, perceptual evaluation of chemosensory subs
Sponsors
Universitätsklinikum der RWTH Aachen
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: from 18 to 55 years - Not taking any medication (antidepressants, neuroleptics) or drugs. - Normal temperature, proof of vaccinated or recovered status regarding COVID.19, or proof of a daily negative test regarding COVID.19.
Exclusion criteria
Exclusion criteria: - Women and men older than 55 - for women: Pregnancy and lactation - smoking - olfactory and respiratory dysfunctions (frequent nosebleeds or nosebleeds experienced within the last 3 days, chronic nasal diseases; upper respiratory tract infections, chronic rhinitis; pulmonary diseases (e.g., asthma, other pulmonary diseases) - diseases with CNS involvement, head injury (e.g. stroke, so-called cerebrovascular insufficiency, multiple sclerosis, traumatic brain injury) - previous operations on head, heart, vessels - metabolic diseases (e.g. diabetes mellitus, pheochromocytoma, hyper- or hypothyroidism) - history of psychiatric disorders (SKID light, BDI for diagnosis) - Other significant medical conditions (e.g., hepatic insufficiency, renal insufficiency, gastric or intestinal ulcers) - acute allergies to food odors and tastes, generally acute food allergies - ingestion of medications or drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The purpose of this study is to characterize a suitable subject sample for planned studies, as well as to optimize the stimuli used. The scents or flavors will not always be presented in the same order so that no order effect occurs. Because previous studies have reported that women and men could smell differently, we will study equal numbers of men and women to detect such an effect. | — |
Secondary
| Measure | Time frame |
|---|---|
| With the help of the proposed screening and pilot study protocol, it should be possible to perform a basal chemosensory characterization of 400 healthy subjects and to create suitable chemosensory stimuli. These subjects and stimuli will then be available for further research. | — |
Countries
Germany
Contacts
Public ContactRea Rodriguez-Raecke
Universitätsklinikum RWTH Aachen
Outcome results
None listed