Psychobiological predictors of the outcome after a neurological inpatient Post-COVID-19-rehabilitation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00028480

Enrollment

120

Registered

2022-03-10

Start date

2022-04-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

U09.9G U10.9G

Interventions

Group 1: Neurological inpatient Post-COVID-19-Rehabilitation (4-6 weeks)

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Ongoing symptoms 12 weeks after Corona infection (Post-COVID-symptoms) - neurological inpatient rehabilitation - age > 18 years - ability to give informed consent

Exclusion criteria

Exclusion criteria: - no Corona infection - symptoms after Corona infection <12 Wochen

Design outcomes

Primary

Measure	Time frame
Subjective illness-related disability duet to Post-Covid-symptoms (adapted Pain Disability Index (PDI) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1)	—

Secondary

Measure	Time frame
- Covid functional status scale (PCFS) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Fatigue (CFS) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Treatment expectations (Generic Rating for Treatment pre-Experiences, Treatment Expectations, and Treatment Effects, G-EEE) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Depression (PHQ-9) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Anxiety (GAD-7) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Somatic Symptoms (PHQ-15) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Health status and medical variables at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Soziodemographic faktors (e.g., age, sex, education) at T0 (start of rehabilitation ) - blood samples (e.g., CRP) at T0 (start of rehabilitation) and T2 (Follow-Up, approx. 3 months after T1) - Neuropsychological variables (concentration, attention, memory) at T0 (start of rehabilitation) and T2 (Follow-Up, approx. 3 months after T1) - Physical status (6 min walk test) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Treatment satisfaction at T1 (end of rehabilitation, 4-6 weeks after T0) and T2 (Follow-Up, approx. 3 months after T1)	—

Measure

Time frame

- Covid functional status scale (PCFS) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Fatigue (CFS) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Treatment expectations (Generic Rating for Treatment pre-Experiences, Treatment Expectations, and Treatment Effects, G-EEE) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Depression (PHQ-9) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Anxiety (GAD-7) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Somatic Symptoms (PHQ-15) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Health status and medical variables at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Soziodemographic faktors (e.g., age, sex, education) at T0 (start of rehabilitation ) - blood samples (e.g., CRP) at T0 (start of rehabilitation) and T2 (Follow-Up, approx. 3 months after T1) - Neuropsychological variables (concentration, attention, memory) at T0 (start of rehabilitation) and T2 (Follow-Up, approx. 3 months after T1) - Physical status (6 min walk test) at T0 (start of rehabilitation), T1 (end of rehabilitation, 4-6 weeks after T0), and T2 (Follow-Up, approx. 3 months after T1) - Treatment satisfaction at T1 (end of rehabilitation, 4-6 weeks after T0) and T2 (Follow-Up, approx. 3 months after T1)

—

Countries

Germany

Contacts

Public ContactChristoph Berwanger

Hardtwaldklinik I Werner Wicker GmbH & Co. KG

berwanger@hwk1.de+495626-87919

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026