Short-term dynamics of circulating free DNA (cfDNA) after pressurized aerosol chemotherapy for peritoneal metastases (PIPAC) in patients with gastric or colon cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00028301

Enrollment

Registered

2025-07-03

Start date

2021-11-16

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C16

Interventions

Group 1: Patients with gastric or colon cancer who have received PIPAC.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with gastric or colon carcinomas and peritoneal carcinomatosis

Exclusion criteria

Exclusion criteria: Infections (HBV, HCV, HIV), systemic diseases, IBD, post-transplantation status.

Design outcomes

Primary

Measure	Time frame
Comparison of the quantity and quality (using mutation detection) of ctDNA in patient blood shortly before and after a PIPAC cycle	—

Secondary

Measure	Time frame
Correlation between changes in ctDNA dynamics after PIPAC and prognosis/overall survival	—

Countries

Germany

Contacts

Public ContactMazen Juratli

Universitätklinikum Münster (UKM)Klinik füt Allgemein-, Viszeral- und TransplantationschirurgieDirektor: Univ.-Prof. Dr. med. A. Pascher, MBA, FEBS

mazen.juratli@ukmuenster.de+492518351403

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026