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Short- and long-term effects of various anti-glaucomatous eye drops on the foveal avascular zone (FAZ)

Short- and long-term effects of various anti-glaucomatous eye drops on the foveal avascular zone (FAZ) - GlaufoVa

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
DRKS
Registry ID
DRKS00028293
Enrollment
180
Registered
2022-03-17
Start date
2022-02-01
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H40.1

Interventions

Group 1: Patients in whom a daily tension profile is carried out under inpatient conditions to evaluate the therapeutic effect. The intraocular pressure should be measured every 3 hours for 3 days. T

Sponsors

Dietrich-Bonhoeffer-KlinikumKlinik für Augenheilkunde
Lead Sponsor

Eligibility

Sex/Gender
All
Age
21 Years to 85 Years

Inclusion criteria

Inclusion criteria: -Patients older than 21 years Patients' willingness to participate in the study and written informed consent. -Diagnosis of primary chronic open-angle glaucoma, pseudoexfoliation glaucoma, ocular hypertension requiring treatment or pigment dispersion glaucoma

Exclusion criteria

Exclusion criteria: Patients with poor general condition or poor compliance -Patients diagnosed with various eye disorders affecting the macular area -Patients with an acute angle-closure situation -Intravenous or oral ingestion of acetazolamide and/or mannitol

Design outcomes

Primary

MeasureTime frame
Determination on the effect of the short-term effect of the eye drop application after 30 minutes and after 60 minutes on vessel density, area, circumference, circular shape of the foveal avascular zone using angio-OCT images

Secondary

MeasureTime frame
Long-term effect (permanently minimized FAZ) of local anti-glaucomatous therapy on patients who needed a renewed tension profile after 6/12 months

Countries

Germany

Contacts

Public ContactUlrike Holland

Dietrich-Bonhoeffer-Klinikum, Klinik für Augenheilkunde

aug-st2@dbknb.de0395/77513427

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026