H40.4
Conditions
Interventions
Group 1: Patients with cytomegalovirus-positive Posner-Schlossman syndrome are examined once by optical coherence tomography angiography. The eye affected by Posner-Schlossman syndrome is compared wit
Sponsors
Charité Campus Virchow-Klinikum
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) proof of Cytomegalovirus-infection in an aqueous humor sample, (2) at least one transient episode of unilateral elevated intraocular pressure (IOP) over 21 mmHg, (3) low-grade anterior uveitis, (4) no iris synechia, (5) no or minimal cells in the anterior chamber.
Exclusion criteria
Exclusion criteria: (1) detection of infection with rubella virus, herpes simplex virus (HSV), or varicella-zoster-virus (VZV) in the aqueous humor samples, (2) refractive errors of the sphere or the cylinder >/= -3.50 dpt, (3) history of retinal disease (diabetic retinopathy, age-related macular degeneration) and (4) amaurosis on the contralateral eye
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| As primary outcome we defined alterations of the vessel area density in different retinal vascular layers, using Optical Coherence Tomography-Angiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are glaucomatous changes measured by Optical Coherence Tomography, differences in the retinal nerve-fiber-layer thickness, endothelial cell density, mean deviation of the perimetry and cup-disc-ratio. | — |
Countries
Germany
Contacts
Public ContactAnna-Karina Maier-Wenzel
Charité – Universitätsmedizin Berlin Campus Virchow Klinikum Klinik für Augenheilkunde
Outcome results
None listed