The influence of alcohol on the pain perception and the endogenous pain modulation in the EEG

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00028262

Enrollment

Registered

2022-02-28

Start date

2022-03-31

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R52.0

Interventions

Group 1: Ethanol, computationally needed amout to reach a blood-alcohol level of one permille (dependent on subjetcs weight and gender) Group 2: Placebo beverage, replaced with water

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: - BMI between 18 and 30 - Experienced in consuming alcohol - Only for women: regular menstruation cycle

Exclusion criteria

Exclusion criteria: - Illness of the central nervous system - Diabetes mellitus - Allergic disposition to alcohol - polyneuropathy - pyschological disorder - Drug abuse - Alcohol dependence - Pregnancy and breastfeeding - Aldehyd-Dehydrogenase polymorphism - Taking painkillers or pychopharmaceuticals

Design outcomes

Primary

Measure	Time frame
evoked potentials as an answer to the pain stimuli, recorded with the EEG	—

Secondary

Measure	Time frame
Evaluation of the pain stimuli with a value between 0 ans 100 on the VAS	—

Countries

Germany

Contacts

Public ContactMara Romero Richter

Fraunhofer ITMPClinical Development and Human Pain Models

mara.romero-richter@itmp.fraunhofer.de069/6301-80244

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026