Prospective observational study for the prediction of organ failure and major postoperative complications after esophagectomy by determination of new biomarkers (DPP3, penKid, bioADM)

Prospective observational study for the prediction of organ failure and major postoperative complications after esophagectomy by determination of new biomarkers (DPP3, penKid, bioADM) - BioEsophagectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00028163

Enrollment

Registered

2022-08-01

Start date

2022-08-01

Completion date

Unknown

Last updated

2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophagectomy

Interventions

Group 1: Patients who undergo esophagectomy will have blood samples analyzed in regard to their levels of pen-Kid, DPP3 and bio-ADM as well es standardized laboratory parameters preoperatively as well

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who undergo an esophagectomy with reconstruction of continuity

Exclusion criteria

Exclusion criteria: - Prgenancy - Minors - inability to consent - patients who are incarcerated or are institutionalized involuntarily by law or authorities

Design outcomes

Primary

Measure	Time frame
Evaluation if there is a correlation between the postoperative dynamic course of the biomarkers bio-ADM, penKid and DPP3 and occurrence of complications following esophagectomy	—

Secondary

Measure	Time frame
Evaluation if there is a difference between the postoperative course of the biomarkers DPP3, penKid and bio-ADM and conventional blood testing in regard to onset of changes in the setting of complications as well as a correlation to the extend of complications.	—

Countries

Germany

Contacts

Public ContactJan Bardenhagen

Universitätsklinikum Hamburg Eppendorf Klinik für Allgemein-, Viszeral- und Thoraxchirurgie

j.bardenhagen@uke.de015222892600

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026