Q25.1
Conditions
Interventions
Group 1: Interventional patients
Therapy: Balloon angioplasty with or without stent placement
Group 2: surgical patients
Therapy: resection with (extended) end-to-end anastomosis
Sponsors
Päd. Kardiologie und Intensivmedizin, OE6730,Medizinische Hochschule Hannover
Eligibility
Sex/Gender
All
Age
0 Days to 12 Months
Inclusion criteria
Inclusion criteria: -Age <12 months old -The patients should have received both echos we plan to analyze and the their therapy at our institution.
Exclusion criteria
Exclusion criteria: Complex congenital heart defects such as: Atrial Septal Defect Atrioventricular Septal Defect Double-outlet Right Ventricle d-Transposition of the Great Arteries Ebstein Anomaly Hypoplastic Left Heart Syndrome Pulmonary Atresia Single Ventricle Tetralogy of Fallot Total Anomalous Pulmonary Venous Return Tricuspid Atresia Truncus Arteriosus Ventricular Septal Defect These defects would make the speckle tracking analysis impossible to perform. Furthermore they are often simultaniously surgically repaired, thus not allowing us to study isolated effects of the coarctation correction. -> Should we have enough* neonates (<30 days old) with isolated aortic coartcation we would like to mostly focus on them, since this is the most typical and most critical in terms of complications and clinical manifestation. * we defined enough as a number of patients that would allow us to also perforn statistical analysis on the collected data. After a power calculation we came up with a number of min.20 patients: at least 10 Patients per group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| longitudinal, radial and circumferential left-ventricular strain and longitudinal right-ventricular strain | — |
Secondary
| Measure | Time frame |
|---|---|
| advanced echocardiographic parameters such as: LVEF, FAC, different diameters and wall thicknesses and different velocities measured at different segments of the aorta etc. | — |
Countries
Germany
Contacts
Public ContactKlea Hysko
Päd.Kardiologie &IntensivmedizinMHH
Outcome results
None listed