Dynamics of circulating tumor DNA (ctDNA) and extracellular vesicle (EVs) for diagnosis, therapy monitoring, and prognosis assessment in solid visceral tumors.

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

DRKS

Registry ID

DRKS00028154

Enrollment

100

Registered

2024-02-16

Start date

2021-11-16

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C15 C18 C19 C22 C23 C24 C25 C26 C49 C16 C48.2

Interventions

Group 1: Blood samples are collected from all patients with solid visceral tumors before tumor resection, 4-7 days after the operation, and 3-6 months post-operation. These blood samples are examined

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: curative intended surgery

Exclusion criteria

Exclusion criteria: Infectivity (HCV, HBV, HIV) CED Condition after transplantation

Design outcomes

Primary

Measure	Time frame
The correlation between ctDNA/EVs dynamics in patients before and after curative-intent surgery with the recurrence rate and overall survival.	—

Secondary

Measure	Time frame
ctDNA/EVs as diagnostic markers in patients with solid visceral tumors.	—

Countries

Germany

Contacts

Public ContactMazen Juratli

Universitätklinikum Münster (UKM) Klinik füt Allgemein-, Viszeral- und Transplantationschirurgie. Direktor: Univ.-Prof. Dr. med. A. Pascher, MBA, FEBS

mazen.juratli@ukmuenster.de+492518351403

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026