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Clinical course, outcome and genetics of inherited arrhythmias in children A multicenter study

Clinical course, outcome and genetics of inherited arrhythmias in children A multicenter study - COGIA

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00028138
Enrollment
500
Registered
2022-03-15
Start date
2022-04-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I49.8 I49 I47.2 I45.8

Interventions

Group 1: Retrospective data collection, observational study of children and adolescents with inherited arrhythmia disorders

Sponsors

Deutsches Herzzentrum München, Technische Universität München
Lead Sponsor

Eligibility

Sex/Gender
All
Age
0 Years to 18 Years

Inclusion criteria

Inclusion criteria: - Age between 0 and less than 18 years - Clinical or genetic diagnosis of congenital arrhythmia syndrome - Clinical or genetic diagnosis of a congenital disorder of the cardiac conduction system

Exclusion criteria

Exclusion criteria: - Presence of structural heart defect - Age of initial diagnosis over 18 years

Design outcomes

Primary

MeasureTime frame
Description of clinical course, molecular genetic etiologies, and outcome of children and adolescents with inherited arrhythmia disorders by collecting data about clinical course, imaging, and outcome.

Secondary

MeasureTime frame
Identification of clinical risk factors for the occurrence of malignant cardiac arrhythmias and for sudden cardiac death / sudden cardiac death equivalent and genotype-phenotype correlation with regard to the course of the disease and the outcome of inherited arrhythmia syndromes in children and adolescents by collecting data on the occurrence of a severe arrhythmia ((non-)sustained ventricular tachycardia in the ECG, long-term ECG or stress test) or sudden cardiac death/equivalent to sudden cardiac death (survived sudden cardiac death, shock caused by ICD, ventricular tachycardia with hemodynamic instability) and result of molecular genetic diagnostics, affected gene and precise localization.

Countries

Germany

Contacts

Public ContactCordula Wolf

Deutsches Herzzentrum München, Technische Universität München

wolf@dhm.mhn.de08912182877

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Sep 1, 2026