Malignant neoplasm of the oral cavity, oropharynx, hypopharynx, larynx C14.8 C10.8 C32.8 C13.8 J39.1
Conditions
Interventions
Group 1: During the operation, regardless of the study, the planned biopsy sites are determined. Before the biopsies are taken, a Raman spectroscopy is carried out at exactly the same places. To do th
Sponsors
Friedrich-Schiller Universität Jena
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patient with primary head and neck cancer in the oral cavity, oropharynx, hypopharynx or larynx, tumor size > 5 mm, written consent to participate in the study OR patients with an inflammatory change in the oral cavity, oropharynx, hypopharynx or larynx > 5 mm, written consent to participate in the study
Exclusion criteria
Exclusion criteria: non
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the measurement properties in vivo with the ex vivo results; security of the investigation | — |
Secondary
| Measure | Time frame |
|---|---|
| Development of an algorithm for in vivo investigation; Investigation of the sensitivity and specificity of the Raman examination for the detection of tumor tissue in differentiation from inflammatory tissue and normal tissue | — |
Countries
Germany
Outcome results
None listed