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Individual characterization of the structure and morphometry of osteogenic cells before and after radiation in patients with head and neck cancer: A contribution to bone physiologic healing processes in compromised patients

Individual characterization of the structure and morphometry of osteogenic cells before and after radiation in patients with head and neck cancer: A contribution to bone physiologic healing processes in compromised patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00028078
Enrollment
30
Registered
2022-02-11
Start date
2022-10-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K08.2

Interventions

Group 1: Rehabilitation 3 months after radiation Group 2: Rehabilitation 6 months after radiation

Sponsors

Charité CVKKlinik für MKG-Chirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Diagnosis of head and neck squamous cell carcinoma that has undergone surgery and/or radiation.

Exclusion criteria

Exclusion criteria: <18 years old, smoker

Design outcomes

Primary

MeasureTime frame
Primary cultures of osteoblasts from the alveolar bone are obtained from the bone samples and examined.—

Secondary

MeasureTime frame
After prosthetic rehabilitation, clinical parameters (mPI, mBI, pocket depth) are evaluated.—

Countries

Germany

Contacts

Public ContactSusanne Nahles

Charité CVK Klinik für MKG-Chirurgie

susanne.nahles@charite.de030450555022

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026