healthy subjects
Conditions
Interventions
Group 1: Subjects are irradiated on the lower back with 60 mJ/cm² 233 nm Far-UVC and with an erythema tester with UVB. Temperature measurement and photo documentation is performed on the 2 irradiated
Sponsors
Charité – Universitätsmedizin Berlin,Department of Dermatology, Venerology and Allergology,Center of Experimental and Applied Cutaneous Physiology (CCP)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: male and female volunteers =18 years without skin diseases written informed consent skin type I–III (Fitzpatrick) Informed about the goal and nature of the study no intensive sun exposure on the skin sites to be irradiated (lower back) in the 14 days prior to the examinations
Exclusion criteria
Exclusion criteria: minors breastfeeding women and women with known pregnancy known skin diseases skin type >III (Fitzpatrick) intensive sun exposure on the skin sites to be irradiated (lower back) in the 14 days prior to the examinations subjects who cannot make decisions independently
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The classical skin parameters erythema formation, transepidermal water loss, skin hydration, elasticity and pH, as well as the activation state of mast cells and macrophages in the skin 24 h after Far-UVC irradiation of 60 mJ/cm² 233 nm do not change. | — |
Secondary
| Measure | Time frame |
|---|---|
| No or negligible DNA damage in the skin occurrs after Far-UVC irradiation of 60 mJ/cm² 233 nm. | — |
Countries
Germany
Contacts
Public ContactMartina Meinke
Charité – Universitätsmedizin Berlin,Department of Dermatology, Venerology and Allergology,Center of Experimental and Applied Cutaneous Physiology (CCP)
Outcome results
None listed