K00.8
Conditions
Interventions
Group 1: Intraoral examination of the patients with subsequent blood analysis.
Sponsors
CharitéCentrum für Zahn-, Mund- und Kieferheilkunde CC 3
Eligibility
Sex/Gender
All
Age
12 Years to No maximum
Inclusion criteria
Inclusion criteria: The patient must be at least 12 years of age, as an asymmetric eruption of the first permanent molars becomes evident (to avoid premature (incorrect) diagnosis of the eruption disorder). Gender does not matter, but must be specified for the evaluation of the genetic analysis. The number of study participants: Spirit. 10 trios with PFE (affected children of two phenotypically healthy or affected parents or affected family members)
Exclusion criteria
Exclusion criteria: Absence of an impacted tooth in the pretherapeutic orthopantomogram (root growth of the teeth that have not yet erupted is not complete). Abnormal tooth germ position, tooth germ malformation, bone deficit in patients with clefts, dilaceration. Syndromic and systemic diseases Teeth that do not erupt due to lack of space.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of this study is to facilitate an easier clinical differential diagnosis of PFE, derive the causes of PFE in the genetic code through genetic analysis and localize the corresponding genes, to optimize or individualize the therapy of PFE based on the results of this study. | — |
Countries
Germany
Contacts
Public ContactTheodosia Bartzela
CharitéCentrum CC03Institut für Zahn-, Mund- und KieferheilkundeAbteilung für Kieferorthopädie, Orthodontie und Kinderzahnmedizin
Outcome results
None listed