Inhalative sedation using isoflurane compare to intravenous sedation in neuro critical care patients

Inhalative sedation using isoflurane compare to intravenous sedation in neuro critical care patients - IsoNICU

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00027950

Enrollment

500

Registered

2022-01-31

Start date

2022-07-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unselected neulogical critical care patients

Interventions

Group 1: isoflurane MAC <1,2. The allocation to the two groups is study-independent and depends on the allocation of treatment places. Both procedures are used equally according to SOP. There is no ra

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Need for sedation, severe cerebral disease, treatment at the neurological intensive care unit

Exclusion criteria

Exclusion criteria: age below 18 years, pregnancy, allergies or contraindication to isoflurane or propfol

Design outcomes

Primary

Measure	Time frame
Comparison of both sedation strategies in reaching the daily intended deep of sedation	—

Secondary

Measure	Time frame
Comparison of both sedation strategies to: the kind of difference to the intended deep of sedation, time of mechanical ventilation, need for additional sedative medication, incidence of delirium, incidence of ventilator-associated pneumonia, varying pupil-diameter, functional outcome, mortality, influence of different neurological illnesses	—

Countries

Germany

Contacts

Public ContactPatrick Schramm

Universitätsklinikum Gießen und Marburg

patrick.schramm@neuro.med.uni-giessen.de004964198545301

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026