SIGnal – Sacroiliac Joints: magnetic resonance investigation, biopsy and immunohistological examination

SIGnal – Sacroiliac Joints: magnetic resonance investigation, biopsy and immunohistological examination - SIGnal

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00027940

Enrollment

Registered

2022-12-23

Start date

2022-09-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M45.0

Interventions

Group 1: MRI, CT with biopsie and questionnaire Group 2: Control biopsy of healthy samples

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: manifest sacroiliitis

Exclusion criteria

Exclusion criteria: Coagulation disorders, allergies, oral anticoagulation, pregnancy, claustrophobia

Design outcomes

Primary

Measure	Time frame
Image findings from the MRI/(DE)CT (e.g. backfill) correlate with the histology.	—

Secondary

Measure	Time frame
The therapy response and predictable based on the cytokine expression pattern and can be seen in the MRI pictures	—

Countries

Germany

Contacts

Public ContactJulian Pohlan

Charité - Universitätsmedizin BerlinKlinik für Radiologie, CCM

julian.pohlan@charite.de+49 30 450 627 006

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026