C18 C22.0
Conditions
Interventions
Group 1: observation group:
As part of routine intraoperative blood samples, antibiotic levels in the blood are determined.
During the hospital stay, the patient file is used to document various data
Sponsors
Universitätsklinik Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients 18 years old or older Planned elective major abdominal surgery Absence of acute or chronic infection Ability of subject to understand character and individual consequences of the clinical study Written informed consent
Exclusion criteria
Exclusion criteria: Patients younger than 18 years of age Absence of an informed consent form Current antibiotic treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical site infections (within 30 days after surgery, according to the CDC criteria) | — |
Secondary
| Measure | Time frame |
|---|---|
| Sepsis within 30 days after surgery Severe Sepsis within 30 days after surgery Frequency of repeated perioperative antibiotic prophylaxis Time between first and second perioperative dose Blood transfusions during the hospital stay Perioperative volume management Antibiotic serum concentration prior to redosing Antibiotic serum concentration prior to closure of the abdomen Other postoperative infections within 30 days after surgery Occurrence of resistant bacteria during postoperative hospital stay Postoperative antibiotic treatment for any condition within 30 days after surgery Blood parameters of inflammation during postoperative hospital stay Length of hospital stay after surgery Re-admission due to infectious complications within 30 days after surgery Total antibiotic cost within 30 days after surgery Total treatment cost within postoperative hospital stay | — |
Countries
Germany
Contacts
Public ContactAnastasia Lemekhova
Universitätsklinik Heidelberg, Abteilung für Allgemein-, Viszeral- und Transplantationschirurgie
Outcome results
None listed