Serum profile of bile acids in critical conditions

Serum profile of bile acids in critical conditions - SeProBACC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00027584

Enrollment

1000

Registered

2022-01-07

Start date

2022-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I60 S06 I62 T07 I63 I21 I38 I51 J44 J18 J80 A41 R57

Interventions

Group 1: critically ill patients Serial blood sampling at three time points within 10 days in the course of illness and determination of the concentration of 15 individual bile acids/conjugation produ

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Female, male, and diverse patients - Age > 18 years - Intracranial hemorrhage (subarachnoid hemorrhage traumatic and spontaneous, subdural hematoma acute and chronic, epidural hematoma, intraparenchymal intracranial hemorrhage) - Trauma (polytrauma, multiple injuries, single injuries) - Stroke (ischemic) - acute myocardial infarction - valvular endocarditis - acute cardiac decompensation - respiratory insufficiency (exacerbated COPD, acute pneumonia of any cause, ARDS) - sepsis of any cause - all forms of shock (hypovolemic, distributive, obstructive, cardiogenic) - Treatment in intensive care units 0119/0116/0041/0141

Exclusion criteria

Exclusion criteria: - Age < 18 years - Lack of consent - Refusal to participate in the study

Design outcomes

Primary

Measure	Time frame
Bile acids in serum at different time points in the course of the disease (observational/descriptive).	—

Countries

Germany

Contacts

Public ContactLars-Olav Harnisch

Universitätsmedizin GöttingenKlinik für Anästhesiologie

lars-olav.harnisch@med.uni-goettingen.de05513963579

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026