Subjective cognitive impairment Mild cognitive impairment Early dementia of different etiology with biomarkers
Conditions
Interventions
Group 1: This is a registry.
By means of various questionnaires and tests, data are generated from participants in relation to early dementia.
Sponsors
Klinik für Neurologie des Uniklinikums Aachen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Ability of the participant and/or his/her legally authorized representative (e.g., spouse or legal guardian), as appropriate and applicable, to understand the purpose and risks of the register and provide signed and dated informed consent and authorization to use protected health information (PHI) in accordance with national and local privacy regulations. - Participating patients must have a diagnosis of SCI, MCI or early dementia of different etiology (i.e. Alzheimer’s Disease, Frontotemporal Dementia, Parkinson’s Disease, Lewy-Body Dementia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Normal Pressure Hydrocephalus, Major Depression; Vascular Dementia; TDP-43 associated limbic encephalopathy (LATE), Mixed Dementia AD + VaD, Prion-Associated Dementia) with biomarkers such as cerebrospinal fluids (CSF) amyloid beta 1-42, amyloid beta 1-40, myloid beta 1-42/amyloid beta 1-40 ratio, total tau and phosphorylated tau, amyloid or tau imaging - At least 18 years of age. Inclusion Criteria for familiy member: -At least 18 years of age. -Patient was included in the registry -Family member is strongly involved to the patient's life according to the patient’s statement -Ability of the participant, as appropriate and applicable, to understand the purpose and risks of the register
Exclusion criteria
Exclusion criteria: - Unwilling to provide informed consent. - No available biomarkers such as cerebrospinal fluids (CSF) amyloid beta 1-42, amyloid beta 1-40, amyloid beta 1-42/amyloid beta 1-40 ratio, total tau and phospho-tau, amyloid or tau imaging. Exclusion Criteria for family member - Unable or unwilling to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To create a registry to collecting longterm data on patients with cognitive impairment and early dementia and the impact of treatments. | — |
Countries
Germany
Contacts
Public ContactJörg B. Schulz
Klinik für Neurologie des Uniklinikums Aachen
Outcome results
None listed