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Clinical results and economic consequences of the endoprosthesis of the knee joint in osteoarthritis and arthritis

Clinical results and economic consequences of the endoprosthesis of the knee joint in osteoarthritis and arthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00027517
Enrollment
346
Registered
2022-01-21
Start date
2021-11-25
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee M17.1

Interventions

Group 1: Patients who received a knee replacement between 2007 and 2019 (minimum follow-up interval 24 months postoperatively) due to osteoarthritis or osteoarthrosis. Open, retrospective observationa

Sponsors

Medizinische Hochschule Hannover - Klinik f. Unfallchirurgie - Sektion Obere Extremtität, Fuß - und Rheumachirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Adults, adults and patients capable of giving consent, of all genders, up to 90 years of age. Primary knee replacement between 2007 and 2019. Follow-up interval of at least 24 months

Exclusion criteria

Exclusion criteria: Age <18 years at the time of the examination, dementia, arthrodesis after endoprosthesis removal, replacement of the prosthesis, arthrodesis of the upper ankle or other location of the foot, growing skeleton, known bone metabolic disorders, paresis.

Design outcomes

Primary

MeasureTime frame
Pain reduction / relief after at least 24 months in both groups (osteoarthritis vs. arthritis (rheumatism)). Evaluation of the existing X-ray images, evaluation of operation data, drug history, follow-up (clinical examination).

Secondary

MeasureTime frame
Change in quality of life post- and preoperatively, economic consequences, subsequent therapies (operative / conservative), time of replacement surgery, change in bone density compared to the healthy foot, influence of the insurance status. Clinical scores (AOFAS, EFAS score, VAS, SF 36, WOMAC, KSS), clinical and radiological examination of the knee joint, bone density measurement, recording of laboratory parameters d. Bone metabolism (calcium, CRP, phosphate, vitamin D level), recording of co-morbidities / risk factors, insurance status.

Countries

Germany

Contacts

Public ContactUlrich Wiebking

Orthopädische Klinik der MHH im Annastift, Departement Fuß - und Sprunggelenk

Wiebking.Ulrich@mh-hannover.de0511/5354/849

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026