Deep brain stimulation evoked potentials as biomarkers in the cortico-basal ganglia network

Deep brain stimulation evoked potentials as biomarkers in the cortico-basal ganglia network - DBS EP Biomarker

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00027504

Enrollment

Registered

2021-12-27

Start date

2022-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20.9

Interventions

Group 1: Preexisting active deep brain stimulation Group 2: Reduction of the frequenz of the deep brain stimulation

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Parkinson's disease, Implanted deep brain stimulation system with electrodes in subthalamic nucleus, written patient consent

Exclusion criteria

Exclusion criteria: Existing scar pathologies or wound healing disorders after previous surgery; further metal implants in the head; pronounced effect fluctuations under existing THS, which would lead to a long-term worsening of symptoms if the stimulation parameters were changed.

Design outcomes

Primary

Measure	Time frame
Measurable deep brain stimulation evoked potentials using a dry electrode EEG system	—

Secondary

Measure	Time frame
Relation between measurable evoked potential and clinical score	—

Countries

Germany

Contacts

Public ContactLukas Goede

Klinik für NeurologieCharité Universitätsmedizin Berlin

lukas.goede@charite.de+49 30 450 660 543

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026