Comparative study of the effectiveness of a mobile destruction unit (Unit DU2100-M2 from MedClair™) of nitrous oxide (N2O) for low-pain delivery in the delivery room

Comparative study of the effectiveness of a mobile destruction unit (Unit DU2100-M2 from MedClair™) of nitrous oxide (N2O) for low-pain delivery in the delivery room - SMILE

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00027493

Enrollment

Registered

2023-10-04

Start date

2022-01-24

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T41.0

Interventions

Group 1: Application of nitrous oxide, exhalation into an anesthesia gas aspiration system Group 2: Application of nitrous oxide, exhalation takes place into the mobile nitrous oxide (N2O) destruction

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Willingness and ability to give consent present - Age: at least 18 years - Good understanding of German - No contraindications for nitrous oxide - Pregnancy without complications - singleton pregnancy - Expected vaginal delivery - Time: opening or expulsion phase of labor with painful, regular contractions

Exclusion criteria

Exclusion criteria: - Lack of informed consent - Multiple pregnancy - Planned cesarean delivery - Contraindications for nitrous oxide - Peridural analgesia catheter (PDA) already in situ

Design outcomes

Primary

Measure	Time frame
Effectiveness of the mobile nitrous oxide (N2O) destruction unit (results of nitrous oxide (N2O) measurements in the delivery room and time-weighted 8-hour exposure mean for delivery room staff (midwives).	—

Secondary

Measure	Time frame
Questionnaires (midwives, patients) about their experiences with the mobile nitrous oxide (N2O) destruction unit.	—

Countries

Germany

Contacts

Public ContactClemens Eichelsbacher

Universitätsmedizin der Johannes Gutenberg-Universität Mainz

Clemens.Eichelsbacher@unimedizin-mainz.de+49 6131 17 4326

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026