Discovery of new biomarkers of heart failure in the exhaled air using ion mobility spectrometry – a prospective cohort study

Discovery of new biomarkers of heart failure in the exhaled air using ion mobility spectrometry – a prospective cohort study - Heart-VOC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00027445

Enrollment

Registered

2021-12-27

Start date

2021-12-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I50.9

Interventions

Group 1: For Patients with acute heart insufficiency coming to the clinic is additionally analysed a breath sample for volatile markers. Group 2: Patients without a hint on chronic heart failure

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: heart insufficiency with symtoms at rest NTproBNP > 2.000 pg/ml written consent of the patient

Exclusion criteria

Exclusion criteria: - severe impairment of lung function with inability to conduct a slow expiratory VC maneuver - lack of cooperation or legal capacity of the patient or suspicion that the necessary data of the patient can not be recorded - Pregnancy - Proven COVID disease

Design outcomes

Primary

Measure	Time frame
evaluation of heart disease dependend Biomarker in exhaled breath	—

Secondary

Measure	Time frame
Practicability for establishing screening for cardiac markers in the exhaled breathe	—

Countries

Germany

Contacts

Public ContactMichael Zänker

Immanuel Klinikum Bernau Herzzentrum Brandenburg Hochschulklinikum der Medizinischen Hochschule Brandenburg

m.zaenker@immanuel.de+49 3338 694410

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026