Healthy subjects with a metabolic risk profile (waist circumference >88 cm in women and >102 cm in men)
Conditions
Interventions
Group 1: During the fibre intervention phase participants consume a drink containing 2 x 5 g citrus fibre twice a day alongside their normal meals.
Each study phase begins with a visit during which du
Sponsors
Technische Universität München Lehrstuhl für Ernährungsmedizin
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: - Providing written informed consent - 35-67 years old - Waist circumference >88 cm (women) and >102 cm (men)
Exclusion criteria
Exclusion criteria: - Not providing written informed consent, - Parallel participation in another interventional study - Chronic diseases: Diabetes mellitus, untreated hypertension (>160/95 mmHg), untreated hormonal diseases (e.g. hyperthyroidism, hypothyroidism), chronic liver diseases (e.g. HBV, HCV), autoimmune diseases (rheumatism, ulcerative colitis, Crohn's disease), chronic infections (e.g. HIV), cardiovascular disease, tumor disease, diverticulosis, - Acute infectious diseases, - Allergy or sensitivity to the study products, - Current dietary fibre supplementation - Pregnancy and breastfeeding, - Having donated blood in the prior 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes of the study are following blood-glucose related parameters: Intervention days: - peak glucose value - time to peak - glucose AUC - shape of the glucose curve 14-day-long intervention phases: - mean glucose values (24 hours, during the day, at night) - mean fasting glucose values - the amount of time in the target blood sugar ("Time in range") - glucose variability | — |
Countries
Germany
Contacts
Public ContactKatarzyna Pietrynik
Technische Universität München Lehrstuhl für Ernährungsmedizin
Outcome results
None listed