Evaluation of the feasibility and validity of scalable self-sampling strategies via finger prick, capillary blood and saliva collection for the detection of anti-SARS-CoV-2 (COVID-19) antibodies

Evaluation of the feasibility and validity of scalable self-sampling strategies via finger prick, capillary blood and saliva collection for the detection of anti-SARS-CoV-2 (COVID-19) antibodies - Self-sampling approaches for the detection of anti-SARS-CoV-2 antibodies

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00027379

Enrollment

150

Registered

2023-01-17

Start date

2021-12-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

U07.1

Interventions

Group 1: Study participants will be asked to come to the study center only once. During this visit, participants will be asked to watch an instructional video and read an instruction leaflet to perfor

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Aged 18 years of age or older - Able to provide a venous blood sample - Able to attend the Tropical Medicine clinic for blood draw - The ability to provide fully informed consent

Exclusion criteria

Exclusion criteria: - Contraindication to venipuncture - Age below 18 years of age - Not able to provide informed consent

Design outcomes

Primary

Measure	Time frame
Head-to-head comparison of the diagnostic accuracy of self-sampling via a finger prick plus capillary blood collection on an absorptive device with finger prick sampling of participants and capillary blood collection on an absorptive device by experienced health care personnel, compared to venous blood collection by venipuncture, the reference standard method for detection of anti-SARS-CoV-2 antibodies.	—

Measure

Time frame

Head-to-head comparison of the diagnostic accuracy of self-sampling via a finger prick plus capillary blood collection on an absorptive device with finger prick sampling of participants and capillary blood collection on an absorptive device by experienced health care personnel, compared to venous blood collection by venipuncture, the reference standard method for detection of anti-SARS-CoV-2 antibodies.

—

Secondary

Measure	Time frame
usability of self-sampling via finger prick and capillary blood collection on an absorptive device in the hands of patients; pre-test the diagnostic accuracy of self-collection of saliva compared to venous blood collection by venipuncture; usability of self-collection of saliva in the hands of patients	—

Countries

Germany

Contacts

Public ContactClaudia Denkinger

Universitätsklinikum Heidelberg Sektion Klinische Tropenmedizin

claudia.denkinger@uni-heidelberg.de+49 6221 56-36637

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026