chronic stress
Conditions
Interventions
Group 1: relaxation hypnosis
Group 2: documentary
Sponsors
Institut für Psychologie und Pädagogik, Universität Ulm
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age at least 18 years; sufficient knowledge of German; good hypnotizability of the subjects (score HGSHS:A = 6; BER: medium to high scores, i.e. 24-48); ability of the subject to give consent; signed consent form. Healthy or health stable subjects; High subjective stress level.
Exclusion criteria
Exclusion criteria: Excludes individuals with acute and past neuropsychiatric disorders or diseases, including Parkinson's disease, Alzheimer's disease, schizophrenia, and substance abuse. Also, individuals with known anemia, immune disorders, autoimmune diseases, acute cancer and diabetes mellitus, and known chronic viral infections such as HIV and hepatitis. Also excluded are individuals who are taking medications with known influence on the immune system, for example immunosuppressants, cytostatics or comparable relevant substance classes, or who have been vaccinated in the past 7 days prior to study inclusion. The intake of iron or vitamin E supplements in a dose of more than 800 IU per day is also an exclusion criterion. Further exclusion criteria are inadequate German language skills and acute mental illnesses
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcomes will be measured using participants' whole blood and immune cells at pre- and post-intervention ATP-turnover-related respiration, uncoupled respiration, and routine respiration will be measured on immune cells using high-resolution respirometry. Mitochondrial density of immune cells will be determined spectrophotometrically. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will include differential blood work and inflammatory parameters (CRP, IL-1beta, IL-6,TNF-alpha) and psychological standardized questionnaires (anxiety, affect, stress). | — |
Countries
Germany
Contacts
Public ContactSarah Karrasch
Institut für Psychologie und Pädagogik, Universität Ulm
Outcome results
None listed