Impact of medical history on the morphologic, histological and molecular-genetic characteristics of intracranial aneurysms

Impact of medical history on the morphologic, histological and molecular-genetic characteristics of intracranial aneurysms - MICRON

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00027349

Enrollment

300

Registered

2023-01-02

Start date

2024-07-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I67.1 I60.9

Interventions

Group 1: Patients meeting inclusion criteria will receive standardized questionnaires on personal background, previous conditions, and previous medical history. Within the clinical routine, tissue sam

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Angiographic detection of an intracranial aneurysm. 2) Microsurgical clipping of the aneurysm with intraoperative sampling from the aneurysm wall.

Exclusion criteria

Exclusion criteria: Missing consent

Design outcomes

Primary

Measure	Time frame
The primary endpoints of this exploratory prospective study are the correlations between immunohistological expression profile in IA wall with: 1. the sociodemographic and medical history of the patients; 2. the radiographic characteristics of the IA (size, morphology, multiple IA, etc.); 3. the rupture status of the IA at initial diagnosis.	—

Secondary

Measure	Time frame
Secondary endpoints include correlations between: 1. histologic markers and radiologic characteristics on diagnostic imaging; 2. radiological characteristics and rupture status; 3. sociomedical history and rupture status.	—

Countries

Germany

Contacts

Public ContactRamazan Jabbarli

Neurosurgeon

ramazan@jabbarli.com01756370955

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026