Missing of 6 or more teeth.
Conditions
Interventions
Group 1: 1) Blood sampling and genetic examination by the Genetics Institute.
2) Dental diagnosis
Sponsors
Charité Zahnklinik
Eligibility
Sex/Gender
All
Age
9 Years to 99 Years
Inclusion criteria
Inclusion criteria: Absence of six or more permanent teeth (excluding wisdom teeth)
Exclusion criteria
Exclusion criteria: Younger than 9 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The aim of the study is to investigate the appearance of patients with oligodontia. For this purpose, the numerical code (Tooth Agenesis Code, TAC) will be used to establish the correlation between the genotype and the phenotype of phenotype of the nongenesis. 2. the genetic material of the patients and their family members (adult siblings, parents or grandparents) will be analyzed according to the genes identified by previous studies. 3. in addition, new genes responsible for hypo /oligodontia (hypodontia: not attachment of 1-5 teeth, oligodontia: 6 or more unattached teeth). (hypodontia: 1-5 teeth not attached, oligodontia: 6 or more teeth not attached), using the whole genome sequencing method. 4. The purpose of the study is to standardize the diagnosis of patients with oligodontia. | — |
Countries
Germany
Contacts
Public ContactJanna Mitscherling
Zahnklinik Charite
Outcome results
None listed