Hepatic steatosis, end-stage liver disease, hepatocellular carcinoma, ascites M62.5
Conditions
Interventions
Group 1: Patients who are evaluated for liver transplant listing with ascites.
Radiological examinations:
- Dual-layer spectral CT to determine the fat content of the liver and abdominal muscles, the
Sponsors
Department of Diagnostic and Interventional Radiology and Nuclear Medicine and Department of Liver Transplantation, University Medical Center Hamburg-Eppendorf
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Evaluation for liver transplant listing. - Clinical indication for a CT scan
Exclusion criteria
Exclusion criteria: - MRI contraindications - Spondylodesis material at the level of the 3rd lumbar vertebra
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients in whom the dual-layer spectral CT fat quantification is applicable versus the number of patients in whom both, dual-layer spectral CT and MRI provide results for the group of patients with and without ascites. Agreement and variance of dual-layer spectral CT and MRI fat quantification results for the liver and the skeletal muscle. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Relationship of the dual-layer spectral CT muscle fat values ??to single-energy CT sarcopenia parameters and to clinical muscle parameters. 2. Relationship of the radiological and clinical parameters to the clinical course and quality of life. | — |
Countries
Germany
Contacts
Public ContactMartina R. Sterneck
Head fo Department of Liver Transplantation
Outcome results
None listed