Mechanistic and clinical effects of the regulation of inhibitory control networks via real-time fMRI neurofeedback in smokers

Mechanistic and clinical effects of the regulation of inhibitory control networks via real-time fMRI neurofeedback in smokers - ImPro

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00027056

Enrollment

Registered

2021-12-20

Start date

2021-06-22

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smokers

Interventions

Group 1: Neurofeedback experimental condition: The participants receive feedback from the inhibitory control network. Group 2: Neurofeedback sham condition: The participants receive feedback from the

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: - Smoke more 10 cigarettes per day for at least 1 year - Good German knowledge

Exclusion criteria

Exclusion criteria: - Severe psychiatric disease - MR contraindications - Pregnancy

Design outcomes

Primary

Measure	Time frame
Changes in inhibitory control performance as measured by Stop Signal task before and after neurofeedback session, using repeated measure ANOVA with the factors ‘Group’ (neurofeedback experimental condition, neurofeedback sham condition) and ‘Time’ (Pre-neurofeedback, Post-neurofeedback)	—

Secondary

Measure	Time frame
- Neurofeedback specific changes in functional connectivity of the target network - Changes in nicotine consumption and impulsivity trait, measured by Fagerstrom Test for Nicotine Dependence (FTND), Barratt Impulsiveness Scale (BIS-11), and UPPS Impulsive Behavior Scale in initial and follow-up (4 weeks later) assessment - Transient changes in resting-state connectivity, measured before and after neurofeedback session?	—

Measure

Time frame

- Neurofeedback specific changes in functional connectivity of the target network - Changes in nicotine consumption and impulsivity trait, measured by Fagerstrom Test for Nicotine Dependence (FTND), Barratt Impulsiveness Scale (BIS-11), and UPPS Impulsive Behavior Scale in initial and follow-up (4 weeks later) assessment - Transient changes in resting-state connectivity, measured before and after neurofeedback session?

—

Countries

Germany

Contacts

Public ContactArezoo Taebi

Universitätsklinikum der RWTH Aachen

ataebi@ukaachen.de+49 241 80 88650

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026