GENERAL HEALTH
Conditions
Interventions
Group 1: Fresh strawberries 500 g/week
Group 2: Fresh strawberries 2500 g/week (first week 1500g, last week 3750g).
Group 3: Fresh strawberries 2500 g/week (first week 1500g, last week 3750g)
Freeze-
Sponsors
Universitätsmedizin Rostock, Institut für Biostatistik und Informatik in Medizin und Alternsforschung
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: • Accessible strawberry salespoint • No or moderate intake of dietary supplements/vitamins • No shift work • Consumption of the tested foods in the past • Weight < 100kg • Regular influenza vaccination (planned but not considered (*)) (*) Citation of ethics application: "Should it be clear at the the start of the study that the recruitment goal cannot be achieved with the given inclusion criteria, the inclusion criteria will be dropped or softened in their order from bottom to top." We could only apply the first 5 criteria.
Exclusion criteria
Exclusion criteria: • known food allergy/intolerance in the subject, food allergy/intolerance to strawberries in the subject or 1st degree relatives; • prescription drugs (except cholesterol-lowering drugs, antihypertensive drugs, thyroid drugs) / severe chronic diseases (e.g. cancer, diabetes, autoimmune diseases).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the biomarkers C-reactive protein (hs-CRP) and LDL cholesterol, as defined in the ethics application dated 4/16/2021. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in other biomarkers (if available): HDL cholesterol, total cholesterol, triglycerides, HOMA-IR, "Phenotypic Age", IL6 & sTNFr1, GDF15, GrimAge, and other exploratory biomarkers (the preceding list was defined in the ethics application dated 04/16/2021). | — |
Countries
Germany
Contacts
Public ContactMichael Walter
Universitätsmedizin Rostock, Institut für Klinische Chemie und Laboratoriumsmedizin
Outcome results
None listed