periodontitis
Conditions
Interventions
Group 1: periodontitis grade B
All patients underwent oral hygiene instructions and professional prophylaxes until full mouth plaque score (PCR) was = 50% (1st step of therapy) [15]. SI was performed
Sponsors
Poliklinik für Parodontologie,ZZMK (Carolinum) der Johann Wolfgang Goethe-Universität Frankfurt a.M.
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: - = 16 years of age - = 20 remaining teeth - written informed consent
Exclusion criteria
Exclusion criteria: - Patients that may require preventive use of systemic antibiotics for measurements that may cause transitory bacteraemia (e.g. pocket probing) - Self-reported chronic disease influencing the serum CRP level (e.g. Rheumatoid Arthritis, Crohn’s Disease or Ulcerative Colitis) - Self-reported infectious disease within the last 8 weeks before examination (history of fever) - Any clinically assessed chronic dermal or mucosal inflammatory condition (e.g. lichen planus) - Nonsurgical or surgical periodontal treatment within the last 24 months before examination - Systemic or topical subgingival antibiotics within the last 8 weeks before examination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum level of neutrophil elastase and CRP; blood sampling prior to non-surgical periodontal treatment (subgingival instrumentation), 1 day, 6 weeks, and 3 months thereafter | — |
Secondary
| Measure | Time frame |
|---|---|
| leukocyte number, serum level of IL-6, IL-8 and LBP; blood sampling prior to non-surgical periodontal treatment (subgingival instrumentation), 1 day, 6 weeks, and 3 months thereafter | — |
Countries
Germany
Contacts
Public ContactPeter Eickholz
Poliklinik für Parodontologie,ZZMK (Carolinum) der Johann Wolfgang Goethe-Universität Frankfurt a.M.
Outcome results
None listed