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Effects of psychosocial stress and performance feedback on pain processing and its neuroendocrine mediation

Effects of psychosocial stress and performance feedback on pain processing and its neuroendocrine mediation - EPSPFPPNM

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00026946
Enrollment
184
Registered
2021-10-29
Start date
2018-09-03
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R52.0

Interventions

Group 1: Trier Social Stress Test (without feedback) Group 2: Trier Social Stress Test with positive feedback Group 3: Trier Social Stress Test with negative feedback Group 4: Placebo Trier Social Str

Sponsors

Universität Würzburg Institut für Psychologie Fakultät für Humanwissenschaften
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: - gender: female - between 18 and 35 years old - being fluent in German

Exclusion criteria

Exclusion criteria: - psychopharmacological or analgesic medication - regular smoking - mental disorders - acute or chronic pain - being a psychology student for more than two semesters

Design outcomes

Primary

MeasureTime frame
The aim was to show potential changes in different pain variables, which were assessed during the experimental procedure four minutes post-TSST (partly in combination with feedback of different valence) and post-recovery (approximately 40 minutes after performing the TSST). A baseline measurement was also collected at the beginning of the experiment as a reference. Pain measurement was based on phasic or tonic heat pain stimuli and can be described as multidimensional, meaning that different pain tests were measured using a thermode (heat pain threshold, heat pain tolerance, temporal summation, ratings of phasic heat pain stimuli) or a combination of the hot water bath circulator and the thermode (conditioned pain modulation of heat pain threshold and ratings of phasic heat pain stimuli). Each pain measurement took approximately 15 minutes.

Secondary

MeasureTime frame
Potential influences of subjective and physiological stress parameters on changes in pain perception were to be recorded. For this purpose, stress ratings and anxiety scores were asked at different measurement points during the experiment. In addition, salivary cortisol and salivary alpha-amylase were determined as objective stress markers. Saliva was collected via salivettes, which were analyzed in a special laboratory. The physiological peaks of these direct (cortisol) or indirect (alpha-amylase as a non-invasive substitute for the determination of catecholamine activity) hormonal parameters were taken into account. Correlations of the subjective parameters post-TSST or the peaks of objective stress parameters were calculated, besides, the time courses of all parameters enumerated here were also used as manipulation checks.

Countries

Germany

Contacts

Public ContactSarah Karen Schneider

Universität WürzburgLehrstuhl für Psychologie I

sarah.k.schneider@uni-wuerzburg.de+49 931 31-89591

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 11, 2026