Intestinal function during critical illnes
Conditions
Interventions
Group 1: Patients with chronic coffee consumption are examined in the first four days of critical illness with organ failure with regard to intestinal function and hemodynamics.
Group 2: Patients with
Sponsors
Charité Campus Benjamin Franklin
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Admission to the ICU within the last 12 hours Existing critical illness, defined by the presence of at least one of the following parameters of organ failure: AKIN II Norepinephrine> 0.05 µg / kg body weight / min GCS 10 qSOFA> 1
Exclusion criteria
Exclusion criteria: • Pregnant / breastfeeding patients • Palliative treatment goal • Known bowel dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first defecation during intensive care therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| • Time to first bowel movement during intensive care therapy • hemodynamic target parameterschange in blood pressure, heart rate and oxygen saturation • Ventilation settings in the case of invasive ventilation as well as parameters of respiration and oxygen supply • Differences in gastric residual volume (GRV) • Differences in abdominal ultrasound (AGUIS, GUTS score) • Differences in routine laboratory controls and inflammatory markers during intensive care treatment • Duration of intensive care treatment / hospital treatment • Frequency of newly occurring organ dysfunctions during intensive care therapy based on the target parameters defined as inclusion criteria. | — |
Countries
Germany
Contacts
Public ContactSascha Treskatsch
Charité Universitätsmedizin Berlin
Outcome results
None listed